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Sorafenib is usually taken 2 times per day. Follow all directions on your prescription label. Do not take Nexavar in larger or smaller amounts or for longer than recommended. Take sorafenib on an empty stomach, at least 1 hour before or 2 hours after eating.

Do not crush, chew, or break a sorafenib tablet. Swallow it whole with water. Your blood pressure will need to be checked often. If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using sorafenib. You may need to stop using the medicine for a short time.

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